Multifaceted Beneficial Effects of Erdosteine: More than a Mucolytic Agent

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Influence of erdosteine, a mucolytic agent, on amoxycillin penetration into sputum in patients with an infective exacerbation of chronic bronchitis.

Twenty four patients with acute infective exacerbations of chronic bronchitis received amoxycillin alone or in combination with erdosteine (a mucolytic agent) for a week in a double blind, placebo controlled study. Clinical assessment scores, body temperature, serum and sputum amoxycillin concentrations, and sputum culture results were recorded in each group. Erdosteine significantly increased ...

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ژورنال

عنوان ژورنال: Drugs

سال: 2020

ISSN: 0012-6667,1179-1950

DOI: 10.1007/s40265-020-01412-x